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what is phosphorylation?

Dear Student,

Phosphorylation is the process by which a phosphate group (PO4) is attached to biomolecules. The process by which ATP is synthesised in the mitochondria is known as oxidative phosphorylation while the process by which ATP is synthesised in the choloplasts during photosynthesis is known as photophosphorylation.

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@Evender

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@ Rahul,

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Phosphorylation is the addition of a phosphate (PO4) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes.

Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2009, the Medline database returns nearly 160,000 articles on the subject, largely on protein phosphorylation).

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The process in cell metabolism by which respiratory enzymes in the mitochondria synthesize ATP from ADP and inorganic phosphate during the oxidation of NADH by molecular oxygen.
 

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