In conversion of affirmative to negative sentence we have to change the meaning of affirmative sentence or not

Dear Student,

While converting an affirmative sentence into a negative sentence, you have to keep in mind that the meaning of the original sentence should not get changed. 
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Yes the meaning changes....
For example
She finished her work (Assertive)
She did not finish her work (Negative)
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I need a proper rule of grammer and as per my knowlege it does not change .
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