Differentiate between Mendelian disorders & chromosomal disorders. Give two examples of each.
Mendelian disorders occur due to muatation or alteration of the genes
they are either dominant or recessive and the trait may be linkes to the s** chromosome or an autosome
eg. haemophilia is s** linked whie phenylketoneuria and sickle cell anemia are autosomal linked recessive traits
Chromosomal disorders occur due to excess, abscence, or abnormal arrangement of chromosomes
a person having an extra or less chromosome is affected there is no such thing such as recessive and dominant because in this case it is the chromosome that is affected while in mendelian disorders it is the genes..
eg. down syndrome, klienfelters syndrome, in both cases the individual has 47 chromosomes and turners syndrome the individual has 45 chromosomes