Can someone explain structure of contractile proteins in simple terms?

Contractile Proteins

  • Actin

    • Actin filament has two F actins (filamentous actins) helically wound around each other.

    • Two filaments of tropomyosin also run close to F actins throughout its length.

    • Troponin is distributed at regular intervals on tropomyosin.

    • Significance of troponin: It masks the binding sites for myosin on actin in resting state.

  • Myosin

    • Myosin is a polymerised protein, i.e., polymer of meromyosins

    • Meromyosin has two parts:
      Globular head with a short arm (Heavy meromyosin; HMM) and a tail (Light meromyosin; LMM)

    • The head and the arm project outwards at a regular distance and angle from each other at the surface of the polymerised myosin and are together called the cross arm.

    • Globular head has ATPase activity.

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