Can someone explain structure of contractile proteins in simple terms?
Contractile Proteins
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Actin
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Actin filament has two F actins (filamentous actins) helically wound around each other.
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Two filaments of tropomyosin also run close to F actins throughout its length.
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Troponin is distributed at regular intervals on tropomyosin.
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Significance of troponin: It masks the binding sites for myosin on actin in resting state.
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Myosin
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Myosin is a polymerised protein, i.e., polymer of meromyosins
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Meromyosin has two parts:
Globular head with a short arm (Heavy meromyosin; HMM) and a tail (Light meromyosin; LMM) -
The head and the arm project outwards at a regular distance and angle from each other at the surface of the polymerised myosin and are together called the cross arm.
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Globular head has ATPase activity.
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